Transgenic Rat Model of Neurodegeneration Caused by Mutation in the TDP Gene

TDP-43 proteinopathies have been observed in a wide range of neurodegenerative diseases. Mutations in the gene encoding TDP-43 (i.e., TDP) have been identified in amyotrophic lateral sclerosis (ALS) and in frontotemporal lobe degeneration associated with motor neuron disease. To study the consequenc...

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Detalhes bibliográficos
Main Authors: Zhou, Hongxia, Huang, Cao, Chen, Han, Wang, Dian, Landel, Carlisle P., Xia, Pedro Yuxing, Bowser, Robert, Liu, Yong-Jian, Xia, Xu Gang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845661/
https://ncbi.nlm.nih.gov/pubmed/20361056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000887
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