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Developing tTA Transgenic Rats for Inducible and Reversible Gene Expression

To develop transgenic lines for conditional expression of desired genes in rats, we generated several lines of the transgenic rats carrying the tetracycline-controlled transactivator (tTA) gene. Using a vigorous, ubiquitous promoter to drive the tTA transgene, we obtained widespread expression of tT...

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Detalhes bibliográficos
Main Authors: Zhou, Hongxia, Huang, Cao, Yang, Min, Landel, Carlisle P, Xia, Pedro Yuxing, Liu, Yong-Jian, Xia, Xu Gang
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640494/
https://ncbi.nlm.nih.gov/pubmed/19214245
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