Allele-Specific Regulation of Matrix Metalloproteinase-3 Gene by Transcription Factor NFκB

BACKGROUND: Matrix metalloproteinase-3 (MMP3) is implicated in the pathogenesis and progression of atherosclerotic lesions. Previous studies suggested that MMP3 expression is influenced by a polymorphism (known as the 5A/6A polymorphism) in the promoter of the MMP3 gene and that this polymorphism is...

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Détails bibliographiques
Auteurs principaux: Souslova, Veronika, Townsend, Paul A., Mann, Jelena, van der Loos, Chris M., Motterle, Anna, D'Acquisto, Fulvio, Mann, Derek A., Ye, Shu
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845631/
https://ncbi.nlm.nih.gov/pubmed/20360864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009902
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