Allele-Specific Regulation of Matrix Metalloproteinase-3 Gene by Transcription Factor NFκB

BACKGROUND: Matrix metalloproteinase-3 (MMP3) is implicated in the pathogenesis and progression of atherosclerotic lesions. Previous studies suggested that MMP3 expression is influenced by a polymorphism (known as the 5A/6A polymorphism) in the promoter of the MMP3 gene and that this polymorphism is...

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Detalhes bibliográficos
Main Authors: Souslova, Veronika, Townsend, Paul A., Mann, Jelena, van der Loos, Chris M., Motterle, Anna, D'Acquisto, Fulvio, Mann, Derek A., Ye, Shu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845631/
https://ncbi.nlm.nih.gov/pubmed/20360864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009902
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