SIRT1 mRNA Expression May Be Associated With Energy Expenditure and Insulin Sensitivity

OBJECTIVE: Sirtuin 1 (SIRT1) is implicated in the regulation of mitochondrial function, energy metabolism, and insulin sensitivity in rodents. No studies are available in humans to demonstrate that SIRT1 expression in insulin-sensitive tissues is associated with energy expenditure and insulin sensit...

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Detalhes bibliográficos
Main Authors: Rutanen, Jarno, Yaluri, Nagendra, Modi, Shalem, Pihlajamäki, Jussi, Vänttinen, Markku, Itkonen, Paula, Kainulainen, Sakari, Yamamoto, Hiroyasu, Lagouge, Marie, Sinclair, David A., Elliott, Peter, Westphal, Christoph, Auwerx, Johan, Laakso, Markku
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844830/
https://ncbi.nlm.nih.gov/pubmed/20107110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1191
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