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Simvastatin Impairs Insulin Secretion by Multiple Mechanisms in MIN6 Cells
Statins are widely used in the treatment of hypercholesterolemia and are efficient in the prevention of cardiovascular disease. Molecular mechanisms explaining statin-induced impairment in insulin secretion remain largely unknown. In the current study, we show that simvastatin decreased glucose-stim...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4641640/ https://ncbi.nlm.nih.gov/pubmed/26561346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142902 |
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