DNA-PKcs plays a dominant role in the regulation of H2AX phosphorylation in response to DNA damage and cell cycle progression

BACKGROUND: When DNA double-strand breaks (DSB) are induced by ionizing radiation (IR) in cells, histone H2AX is quickly phosphorylated into γ-H2AX (p-S139) around the DSB site. The necessity of DNA-PKcs in regulating the phosphorylation of H2AX in response to DNA damage and cell cycle progression w...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: An, Jing, Huang, Yue-Cheng, Xu, Qing-Zhi, Zhou, Li-Jun, Shang, Zeng-Fu, Huang, Bo, Wang, Yu, Liu, Xiao-Dan, Wu, De-Chang, Zhou, Ping-Kun
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Research article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844398/
https://ncbi.nlm.nih.gov/pubmed/20205745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-11-18
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars