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Inhibition of Lung Fluid Clearance and Epithelial Na(+) Channels by Chlorine, Hypochlorous Acid, and Chloramines
We investigated the mechanisms by which chlorine (Cl(2)) and its reactive byproducts inhibit Na(+)-dependent alveolar fluid clearance (AFC) in vivo and the activity of amiloride-sensitive epithelial Na(+) channels (ENaC) by measuring AFC in mice exposed to Cl(2) (0–500 ppm for 30 min) and Na(+) and...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2843221/ https://ncbi.nlm.nih.gov/pubmed/20106988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.073981 |
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