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α(1)-Antitrypsin Inhibits Epithelial Na(+) Transport In Vitro and In Vivo

A variety of studies have shown that Na(+) reabsorption across epithelial cells depends on the protease–antiprotease balance. Herein, we investigate the mechanisms by which α(1)-antitrypsin (A1AT), a major anti-serine protease in human plasma and lung epithelial fluid and lacking a Kunitz domain, re...

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Detalhes bibliográficos
Main Authors: Lazrak, Ahmed, Nita, Izabella, Subramaniyam, Devipriya, Wei, Shipeng, Song, Weifeng, Ji, Hong-Long, Janciauskiene, Sabina, Matalon, Sadis
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742747/
https://ncbi.nlm.nih.gov/pubmed/19131639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0384OC
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