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G protein subunit Gα(13) binds to integrin α(IIb)β(3) and mediates integrin “outside-in” signaling
Integrins mediate cell adhesion to the extracellular matrix and transmit signals within the cell that stimulate cell spreading, retraction, migration, and proliferation. The mechanism of integrin outside-in signaling has been unclear. We found that the heterotrimeric guanine nucleotide-binding prote...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2842917/ https://ncbi.nlm.nih.gov/pubmed/20075254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1174779 |
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