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Inhibition of PHOSPHO1 activity results in impaired skeletal mineralization during limb development of the chick
PHOSPHO1 is a bone specific phosphatase implicated in the initiation of inorganic phosphate generation for matrix mineralization. The control of mineralization is attributed to the actions of tissue-non specific alkaline phosphatase (TNAP). However, matrix vesicles (MVs) containing apatite crystals...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2842458/ https://ncbi.nlm.nih.gov/pubmed/20053388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2009.12.018 |
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