Inhibition of PHOSPHO1 activity results in impaired skeletal mineralization during limb development of the chick

PHOSPHO1 is a bone specific phosphatase implicated in the initiation of inorganic phosphate generation for matrix mineralization. The control of mineralization is attributed to the actions of tissue-non specific alkaline phosphatase (TNAP). However, matrix vesicles (MVs) containing apatite crystals...

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Hlavní autoři: MacRae, Vicky E., Davey, Megan G., McTeir, Lynn, Narisawa, Sonoko, Yadav, Manisha C., Millan, Jose Luis, Farquharson, Colin.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842458/
https://ncbi.nlm.nih.gov/pubmed/20053388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2009.12.018
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