Affinity maturation of human botulinum neurotoxin antibodies by light chain shuffling via yeast mating

Botulism is caused by the botulinum neurotoxins (BoNTs), the most poisonous substance known. Because of the high potency of BoNT, development of diagnostic and therapeutic antibodies for botulism requires antibodies of very high affinity. Here we report the use of yeast mating to affinity mature BoN...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Lou, J., Geren, I., Garcia-Rodriguez, C., Forsyth, C.M., Wen, W., Knopp, K., Brown, J., Smith, T., Smith, L.A., Marks, J.D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841544/
https://ncbi.nlm.nih.gov/pubmed/20156888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzq001
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados