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Allosteric gating of Son of sevenless activity by the histone domain

Regulated activation of Ras by receptor tyrosine kinases (RTK) constitutes a key transduction step in signaling processes that control an array of fundamental cellular functions including proliferation, differentiation, and survival. The principle mechanism by which Ras is activated down stream of R...

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Autores principales: Yadav, Kamlesh K., Bar-Sagi, Dafna
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840464/
https://ncbi.nlm.nih.gov/pubmed/20133694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914315107
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