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Discovery of a distinct domain in cyclin A sufficient for centrosomal localization independently of Cdk binding

Centrosomes have recently emerged as key regulators of the cell cycle. The G1/S transition requires a functional centrosome, and centrosomal localization of numerous proteins, including cyclin/Cdk complexes, is important for the G2/M transition. Here we identify a modular centrosomal localization si...

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Detalhes bibliográficos
Main Authors: Pascreau, Gaetan, Eckerdt, Frank, Churchill, Mair E. A., Maller, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840291/
https://ncbi.nlm.nih.gov/pubmed/20133761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914874107
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