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The cyclin A centrosomal localization sequence recruits MCM5 and Orc1 to regulate centrosome reduplication
Centrosomes are the major microtubule-organizing centers in animal cells and regulate formation of a bipolar mitotic spindle. Aberrant centrosome number causes chromosome mis-segregation, and has been implicated in genomic instability and tumor development. Previous studies have demonstrated a role...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2915877/ https://ncbi.nlm.nih.gov/pubmed/20663915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.073098 |
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