Hinge Residue I174 is Critical for Proper dNTP Selection by DNA Polymerase β

DNA polymerase β (pol β) is the key gap-filling polymerase in base excision repair, the DNA repair pathway responsible for repairing up to 20,000 endogenous lesions per cell per day. Pol β is also widely used as a model polymerase for structure and function studies and several structural regions hav...

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Hlavní autoři: Yamtich, Jen, Starcevic, Daniela, Lauper, Julia, Smith, Elenoe, Shi, Idina, Rangarajan, Sneha, Jaeger, Joachim, Sweasy, Joann B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840207/
https://ncbi.nlm.nih.gov/pubmed/20108981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901735a
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