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Hinge Residue I174 is Critical for Proper dNTP Selection by DNA Polymerase β
DNA polymerase β (pol β) is the key gap-filling polymerase in base excision repair, the DNA repair pathway responsible for repairing up to 20,000 endogenous lesions per cell per day. Pol β is also widely used as a model polymerase for structure and function studies and several structural regions hav...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840207/ https://ncbi.nlm.nih.gov/pubmed/20108981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901735a |
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