טוען...
Amyloidogenic light chains induce cardiomyocyte contractile dysfunction and apoptosis via a non-canonical p38α MAPK pathway
Patients with primary (AL) cardiac amyloidosis suffer from progressive cardiomyopathy with a median survival of less than 8 months and a 5-year survival of <10%. Contributing to this poor prognosis is the fact that these patients generally do not tolerate standard heart failure therapies. The mol...
שמור ב:
Main Authors: | , , , , , , , , , , , , |
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פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
National Academy of Sciences
2010
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840082/ https://ncbi.nlm.nih.gov/pubmed/20150510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912263107 |
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