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Human amyloidogenic light chain proteins result in cardiac dysfunction, cell death, and early mortality in zebrafish
Systemic amyloid light-chain (AL) amyloidosis is associated with rapidly progressive and fatal cardiomyopathy resulting from the direct cardiotoxic effects of circulating AL light chain (AL-LC) proteins and the indirect effects of AL fibril tissue infiltration. Cardiac amyloidosis is resistant to st...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Physiological Society
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3727100/ https://ncbi.nlm.nih.gov/pubmed/23624626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00186.2013 |
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