Stanniocalcin1 is a key mediator of amyloidogenic light chain induced cardiotoxicity

Immunoglobulin light chain (LC) amyloidosis (AL) results from overproduction of circulating amyloidogenic LC proteins and subsequent amyloid fibril deposition in organs. Mortality in AL amyloidosis patients is highly associated with a rapidly progressive AL cardiomyopathy, marked by profound impairm...

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Detalhes bibliográficos
Main Authors: Guan, Jian, Mishra, Shikha, Shi, Jianru, Plovie, Eva, Qiu, Yiling, Cao, Xin, Gianni, Davide, Jiang, Bingbing, del Monte, Federica, Connors, Lawreen H., Seldin, David C., Lavatelli, Francesca, Rognoni, Paola, Palladini, Giovanni, Merlini, Giampaolo, Falk, Rodney H., Semigran, Marc J., Dec, G. William, MacRae, Calum A., Liao, Ronglih
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914405/
https://ncbi.nlm.nih.gov/pubmed/23982491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-013-0378-5
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