Stanniocalcin1 is a key mediator of amyloidogenic light chain induced cardiotoxicity

Immunoglobulin light chain (LC) amyloidosis (AL) results from overproduction of circulating amyloidogenic LC proteins and subsequent amyloid fibril deposition in organs. Mortality in AL amyloidosis patients is highly associated with a rapidly progressive AL cardiomyopathy, marked by profound impairm...

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Hlavní autoři: Guan, Jian, Mishra, Shikha, Shi, Jianru, Plovie, Eva, Qiu, Yiling, Cao, Xin, Gianni, Davide, Jiang, Bingbing, del Monte, Federica, Connors, Lawreen H., Seldin, David C., Lavatelli, Francesca, Rognoni, Paola, Palladini, Giovanni, Merlini, Giampaolo, Falk, Rodney H., Semigran, Marc J., Dec, G. William, MacRae, Calum A., Liao, Ronglih
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914405/
https://ncbi.nlm.nih.gov/pubmed/23982491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-013-0378-5
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