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Homocysteine Induces Cardiomyocyte Dysfunction and Apoptosis through p38 MAPK-Mediated Increase in Oxidant Stress
Elevated plasma homocysteine (Hcy) is a risk factor for cardiovascular disease. While Hcy has been shown to promote endothelial dysfunction by decreasing the bioavailability of nitric oxide and increasing oxidative stress in the vasculature, the effects of Hcy on cardiomyocytes remain less understoo...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3294144/ https://ncbi.nlm.nih.gov/pubmed/22227328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2011.12.009 |
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