Homocysteine Induces Cardiomyocyte Dysfunction and Apoptosis through p38 MAPK-Mediated Increase in Oxidant Stress

Elevated plasma homocysteine (Hcy) is a risk factor for cardiovascular disease. While Hcy has been shown to promote endothelial dysfunction by decreasing the bioavailability of nitric oxide and increasing oxidative stress in the vasculature, the effects of Hcy on cardiomyocytes remain less understoo...

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Detaylı Bibliyografya
Asıl Yazarlar: Wang, Xu, Cui, Lei, Joseph, Jacob, Jiang, Bingbing, Pimental, David, Handy, Diane E., Liao, Ronglih, Loscalzo, Joseph
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294144/
https://ncbi.nlm.nih.gov/pubmed/22227328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2011.12.009
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