A point mutation in the MET oncogene abrogates metastasis without affecting transformation

The MET oncogene encodes the tyrosine kinase receptor for hepatocyte growth factor/scatter factor (HGF), known to stimulate invasive growth of epithelial cells. MET is overexpressed in a significant percentage of human cancers and is amplified during the transition between primary tumors and metasta...

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Detaylı Bibliyografya
Asıl Yazarlar: Giordano, Silvia, Bardelli, Alberto, Zhen, Zhu, Menard, Sylvie, Ponzetto, Carola, Comoglio, Paolo M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences of the USA 1997
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC28399/
https://ncbi.nlm.nih.gov/pubmed/9391119
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