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Differential Transduction Following Basal Ganglia Administration of Distinct Pseudotyped AAV Capsid Serotypes in Nonhuman Primates

We examined the transduction efficiency of different adeno-associated virus (AAV) capsid serotypes encoding for green fluorescent protein (GFP) flanked by AAV2 inverted terminal repeats in the nonhuman primate basal ganglia as a prelude to translational studies, as well as clinical trials in patient...

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Détails bibliographiques
Auteurs principaux: Dodiya, Hemraj B, Bjorklund, Tomas, Stansell III, James, Mandel, Ronald J, Kirik, Deniz, Kordower, Jeffrey H
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839447/
https://ncbi.nlm.nih.gov/pubmed/19773746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.216
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