Efficient Gene Delivery and Selective Transduction of Glial Cells in the Mammalian Brain by AAV Serotypes Isolated From Nonhuman Primates

Adeno-associated viral (AAV) vectors have become the primary delivery agent for somatic gene transfer into the central nervous system (CNS). To date, AAV-mediated gene delivery to the CNS is based on serotypes 1–9, with efficient gene transfer to neurons only—selective and widespread transduction of...

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Bibliografiske detaljer
Main Authors: Lawlor, Patricia A, Bland, Ross J, Mouravlev, Alexandre, Young, Deborah, During, Matthew J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2009
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835020/
https://ncbi.nlm.nih.gov/pubmed/19638961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.170
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