AAV-S: A versatile capsid variant for transduction of mouse and primate inner ear

Gene therapy strategies using adeno-associated virus (AAV) vectors to treat hereditary deafnesses have shown remarkable efficacy in some mouse models of hearing loss. Even so, there are few AAV capsids that transduce both inner and outer hair cells—the cells that express most deafness genes—and fewe...

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Bibliografische gegevens
Gepubliceerd in:Mol Ther Methods Clin Dev
Hoofdauteurs: Ivanchenko, Maryna V., Hanlon, Killian S., Hathaway, Daniel M., Klein, Alex J., Peters, Cole W., Li, Yaqiao, Tamvakologos, Panos I., Nammour, Josette, Maguire, Casey A., Corey, David P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Gene & Cell Therapy 2021
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8044388/
https://ncbi.nlm.nih.gov/pubmed/33869656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2021.03.019
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