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AAV-S: A versatile capsid variant for transduction of mouse and primate inner ear
Gene therapy strategies using adeno-associated virus (AAV) vectors to treat hereditary deafnesses have shown remarkable efficacy in some mouse models of hearing loss. Even so, there are few AAV capsids that transduce both inner and outer hair cells—the cells that express most deafness genes—and fewe...
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| 出版年: | Mol Ther Methods Clin Dev |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Gene & Cell Therapy
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8044388/ https://ncbi.nlm.nih.gov/pubmed/33869656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2021.03.019 |
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