AAV-S: A versatile capsid variant for transduction of mouse and primate inner ear

Gene therapy strategies using adeno-associated virus (AAV) vectors to treat hereditary deafnesses have shown remarkable efficacy in some mouse models of hearing loss. Even so, there are few AAV capsids that transduce both inner and outer hair cells—the cells that express most deafness genes—and fewe...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Mol Ther Methods Clin Dev
Asıl Yazarlar: Ivanchenko, Maryna V., Hanlon, Killian S., Hathaway, Daniel M., Klein, Alex J., Peters, Cole W., Li, Yaqiao, Tamvakologos, Panos I., Nammour, Josette, Maguire, Casey A., Corey, David P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Gene & Cell Therapy 2021
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8044388/
https://ncbi.nlm.nih.gov/pubmed/33869656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2021.03.019
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller