Microbial Induction of Inflammatory Bowel Disease Associated Gene TL1A (TNFSF15) in Antigen Presenting Cells

TL1A is a member of the TNF superfamily and its expression is increased in the mucosa of inflammatory bowel disease (IBD) patients. Neutralizing anti-mouse TL1A Ab attenuates chronic colitis in two T cell driven murine models, suggesting that TL1A is a central modulator of gut mucosal inflammation i...

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Hauptverfasser: Shih, David Q., Kwan, Lola Y., Chavez, Valerie, Cohavy, Offer, Gonsky, Rivkah, Chang, Elmer Y., Chang, Christopher, Elson, Charles O., Targan, Stephan R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839414/
https://ncbi.nlm.nih.gov/pubmed/19839006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200839087
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