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Multiple activating and repressive cis-promoter regions regulate TNFSF15 expression in human primary mononuclear cells

TL1A/TNFSF15 has been associated with IBD (inflammatory bowel disease) in GWAS (genome-wide association study) and plays a role mediating mucosal inflammation in IBD. Higher TL1A expression is associated with disease severity in both patients and mouse models. Although TL1A has been studied extensiv...

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Detalhes bibliográficos
Main Authors: Gonsky, Rivkah, Deem, Richard L., Targan, Stephan R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889718/
https://ncbi.nlm.nih.gov/pubmed/23642711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2013.04.004
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