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Multiple activating and repressive cis-promoter regions regulate TNFSF15 expression in human primary mononuclear cells
TL1A/TNFSF15 has been associated with IBD (inflammatory bowel disease) in GWAS (genome-wide association study) and plays a role mediating mucosal inflammation in IBD. Higher TL1A expression is associated with disease severity in both patients and mouse models. Although TL1A has been studied extensiv...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3889718/ https://ncbi.nlm.nih.gov/pubmed/23642711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2013.04.004 |
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