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Efflux-Pump Derived Multiple Drug Resistance to Ethambutol Monotherapy in Mycobacterium tuberculosis and Ethambutol Pharmacokinetics-Pharmacodynamics
BACKGROUND: In the treatment of tuberculosis, ethambutol is used in case there is isoniazid resistance. We examined for the emergence of drug resistance to ethambutol monotherapy in pharmacokinetic-pharmacodynamic studies in the hollow fiber system. METHODS: Dose–effect studies and dose-scheduling s...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2838947/ https://ncbi.nlm.nih.gov/pubmed/20210628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/651377 |
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