AMP-activated Protein Kinase Signaling Activation by Resveratrol Modulates Amyloid-β Peptide Metabolism

Alzheimer disease is an age-related neurodegenerative disorder characterized by amyloid-β (Aβ) peptide deposition into cerebral amyloid plaques. The natural polyphenol resveratrol promotes anti-aging pathways via the activation of several metabolic sensors, including the AMP-activated protein kinase...

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Main Authors: Vingtdeux, Valérie, Giliberto, Luca, Zhao, Haitian, Chandakkar, Pallavi, Wu, Qingli, Simon, James E., Janle, Elsa M., Lobo, Jessica, Ferruzzi, Mario G., Davies, Peter, Marambaud, Philippe
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Neurobiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838330/
https://ncbi.nlm.nih.gov/pubmed/20080969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.060061
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