Novel synthetic small-molecule activators of AMPK as enhancers of autophagy and amyloid-β peptide degradation

AMP-activated protein kinase (AMPK) is a metabolic sensor involved in intracellular energy metabolism through the control of several homeostatic mechanisms, which include autophagy and protein degradation. Recently, we reported that AMPK activation by resveratrol promotes autophagy-dependent degrada...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Vingtdeux, Valérie, Chandakkar, Pallavi, Zhao, Haitian, d'Abramo, Cristina, Davies, Peter, Marambaud, Philippe
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Federation of American Societies for Experimental Biology 2011
Pynciau:
Research Communications
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005419/
https://ncbi.nlm.nih.gov/pubmed/20852062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-167361
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