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NMDA receptor activation and nitroxidative regulation of the glutamatergic pathway during nociceptive processing

The role of peroxynitrite (PN) as a mediator of nociceptive signaling is emerging. We recently reported that the development of central sensitization that follows the intraplantar injection of carrageenan in rats is associated with spinal PN synthesis. We now demonstrate that a significant pathway t...

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Hlavní autoři: Chen, Zhoumo, Muscoli, Carolina, Doyle, Tim, Bryant, L., Cuzzocrea, Salvatore, Mollace, Vincenzo, Mastroianni, Rosanna, Masini, Emanuela, Salvemini, Daniela
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837917/
https://ncbi.nlm.nih.gov/pubmed/20167432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2010.01.015
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