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Structural consequences of a 3′ → 3′ DNA interstrand cross-link by a trinuclear platinum complex: unique formation of two such cross-links in a 10-mer duplex
Combined multidimensional nuclear magnetic resonance spectroscopy and electrospray mass spectrometry was used to analyze the platinated DNA adduct of the phase II anticancer drug [{trans-PtCl(NH(3))(2)}(2)-μ-{trans-Pt(NH(3))(2)(NH(2)(CH(2))(6)NH(2))(2)}](NO(3))(4) (BBR3464) with [5′-d(ACG*TATACG*T)-...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2837598/ https://ncbi.nlm.nih.gov/pubmed/19415349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-009-0509-5 |
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