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CD137 agonist antibody prevents cancer recurrence: contribution of CD137 on both hematopoietic and nonhematopoietic cells

Antigen-specific memory T cells (Tms) are essential in the immune surveillance of residual and metastatic tumors. Activation of Tms requires designing vaccines based on tumor rejection antigens, which are often not available to cancer patients. Therefore, it is desirable to have a general applicable...

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Autors principals: Narazaki, Hidehiko, Zhu, Yuwen, Luo, Liqun, Zhu, Gefeng, Chen, Lieping
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837330/
https://ncbi.nlm.nih.gov/pubmed/20068221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-192591
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