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Direct contacts between extracellular membrane-proximal domains are required for VEGF receptor activation and cell signaling
Structural analyses of the extracellular region of stem cell factor (SCF) receptor (also designated KIT) in complex with SCF revealed a sequence motif in a loop in the fourth Ig-like domain (D4) that is responsible for forming homotypic receptor contacts and for ligand-induced KIT activation and cel...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2836632/ https://ncbi.nlm.nih.gov/pubmed/20080685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914052107 |
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