Llwytho...
The Strength And Cooperativity of Contacts in KIT Extracellular Domain Determine Normal Ligand Dependent Stimulation or Oncogenic Activation in Cancer
The receptor tyrosine kinase KIT plays an important role in development of germ cells, hematopoietic cells and interstitial pacemaker cells. Oncogenic KIT mutations play an important `driver' role in gastrointestinal stromal tumors, acute myeloid leukemias and melanoma among other cancers. Here...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Mol Cell |
|---|---|
| Prif Awduron: | , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2014
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4764128/ https://ncbi.nlm.nih.gov/pubmed/25544564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.11.021 |
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