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Direct contacts between extracellular membrane-proximal domains are required for VEGF receptor activation and cell signaling

Structural analyses of the extracellular region of stem cell factor (SCF) receptor (also designated KIT) in complex with SCF revealed a sequence motif in a loop in the fourth Ig-like domain (D4) that is responsible for forming homotypic receptor contacts and for ligand-induced KIT activation and cel...

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書目詳細資料
Main Authors: Yang, Yan, Xie, Peng, Opatowsky, Yarden, Schlessinger, Joseph
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836632/
https://ncbi.nlm.nih.gov/pubmed/20080685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914052107
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