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Mutational Analysis of Threonine 402 Adjacent to the GXXXG Dimerization Motif in TM1 of ABCG2
ABCG2 is an ATP-binding cassette half-transporter important in normal tissue protection, drug distribution and excretion. ABCG2 requires homodimerization for function, though the mechanism for dimerization has not been elucidated. We carried out mutational analysis of threonine 402, three residues a...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2836409/ https://ncbi.nlm.nih.gov/pubmed/20088606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi902085q |
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