Mutational Analysis of Threonine 402 Adjacent to the GXXXG Dimerization Motif in TM1 of ABCG2

ABCG2 is an ATP-binding cassette half-transporter important in normal tissue protection, drug distribution and excretion. ABCG2 requires homodimerization for function, though the mechanism for dimerization has not been elucidated. We carried out mutational analysis of threonine 402, three residues a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Polgar, Orsolya, Ierano, Caterina, Tamaki, Akina, Stanley, Bradford, Ward, Yvona, Xia, Di, Tarasova, Nadya, Robey, Robert W., Bates, Susan E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836409/
https://ncbi.nlm.nih.gov/pubmed/20088606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi902085q
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge