A locus on distal Chromosome 11 (ahl8) and its interaction with Cdh23(ahl) underlie the early onset, age-related hearing loss of DBA/2J mice

The DBA/2J inbred strain of mice is used extensively in hearing research, yet little is known about the genetic basis for its early onset, progressive hearing loss. To map underlying genetic factors we analyzed recombinant inbred strains and linkage backcrosses. Analysis of 213 mice from 31 BXD reco...

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Hauptverfasser: Johnson, Kenneth R., Longo-Guess, Chantal, Gagnon, Leona H., Yu, Heping, Zheng, Qing Yin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836023/
https://ncbi.nlm.nih.gov/pubmed/18662770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2008.06.007
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