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A locus on distal Chromosome 11 (ahl8) and its interaction with Cdh23(ahl) underlie the early onset, age-related hearing loss of DBA/2J mice

The DBA/2J inbred strain of mice is used extensively in hearing research, yet little is known about the genetic basis for its early onset, progressive hearing loss. To map underlying genetic factors we analyzed recombinant inbred strains and linkage backcrosses. Analysis of 213 mice from 31 BXD reco...

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Detalhes bibliográficos
Main Authors: Johnson, Kenneth R., Longo-Guess, Chantal, Gagnon, Leona H., Yu, Heping, Zheng, Qing Yin
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836023/
https://ncbi.nlm.nih.gov/pubmed/18662770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2008.06.007
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