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A locus on distal Chromosome 10 (ahl4) affecting age-related hearing loss in A/J mice

The ahl locus, shown to be a strain-specific Cdh23 dimorphism, contributes to age-related hearing loss in many inbred mouse strains. A/J mice begin to lose hearing by four weeks of age, much earlier than C57BL/6J (B6) mice, although both strains have the same Cdh23(ahl) variant. Here, we use recombi...

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Detalhes bibliográficos
Main Authors: Zheng, Qing Yin, Ding, Dalian, Yu, Heping, Salvi, Richard J., Johnson, Kenneth R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756338/
https://ncbi.nlm.nih.gov/pubmed/18280008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2007.12.011
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