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A QTL on Chr 5 modifies hearing loss associated with the fascin-2 variant of DBA/2J mice

Inbred mouse strains serve as important models for human presbycusis or age-related hearing loss. We previously mapped a locus (ahl8) contributing to the progressive hearing loss of DBA/2J (D2) mice and later showed that a missense variant of the Fscn2 gene, unique to the D2 inbred strain, was respo...

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Vydáno v:Mamm Genome
Hlavní autoři: Johnson, Kenneth R., Longo-Guess, Chantal M., Gagnon, Leona H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629822/
https://ncbi.nlm.nih.gov/pubmed/26092689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-015-9574-y
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