A dinucleotide motif in oligonucleotides shows potent immunomodulatory activity and overrides species-specific recognition observed with CpG motif

Схожие документы

• ‘Immunomers’—novel 3′–3′-linked CpG oligodeoxyribonucleotides as potent immunomodulatory agents
  по: Yu, Dong, et al.
  Опубликовано: (2002)
• Immunomodulatory oligonucleotides containing a cytosine-phosphate-2′-deoxy-7-deazaguanosine motif as potent Toll-like receptor 9 agonists
  по: Kandimalla, Ekambar R., et al.
  Опубликовано: (2005)
• Divergent synthetic nucleotide motif recognition pattern: design and development of potent immunomodulatory oligodeoxyribonucleotide agents with distinct cytokine induction profiles
  по: Kandimalla, Ekambar R., et al.
  Опубликовано: (2003)
• Immune-Stimulatory Dinucleotide at the 5′-End of Oligodeoxynucleotides Is Critical for TLR9-Mediated Immune Responses
  по: Putta, Mallikarjuna R., et al.
  Опубликовано: (2013)
• Design, synthesis and biological evaluation of novel antagonist compounds of Toll-like receptors 7, 8 and 9
  по: Kandimalla, Ekambar R., et al.
  Опубликовано: (2013)