Novel chimeric immunomodulatory compounds containing short CpG oligodeoxyribonucleotides have differential activities in human cells

Immunostimulatory DNA sequences (ISS) containing CpG motifs induce interferon-α (IFN-α) and interferon-γ (IFN-γ) from human peripheral blood mononuclear cells and stimulate human B cells to proliferate and produce IL-6. We studied the motif and structural requirements for both types of activity usin...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Marshall, Jason D., Hessel, Edith M., Gregorio, Josh, Abbate, Christina, Yee, Priscilla, Chu, Mabel, Nest, Gary Van, Coffman, Robert L., Fearon, Karen L.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2003
Assuntos:	Articles
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC212800/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12930963/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg700
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