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Myosin IIA associates with NK cell lytic granules to enable their interaction with F-actin and function at the immunological synapse
NK cell cytotoxicity requires the formation of an actin-rich immunological synapse (IS) with a target cell and the polarization of perforin-containing lytic granules toward the IS. Following the polarization of lytic granules, they traverse through the actin-rich IS to join the NK cell membrane in o...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2835774/ https://ncbi.nlm.nih.gov/pubmed/19454694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0804337 |
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