Myosin IIA associates with NK cell lytic granules to enable their interaction with F-actin and function at the immunological synapse

NK cell cytotoxicity requires the formation of an actin-rich immunological synapse (IS) with a target cell and the polarization of perforin-containing lytic granules toward the IS. Following the polarization of lytic granules, they traverse through the actin-rich IS to join the NK cell membrane in o...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sanborn, Keri B., Rak, Gregory D., Maru, Saumya Y., Demers, Korey, Difeo, Analisa, Martignetti, John A, Betts, Michael R., Favier, Rémi, Banerjee, Pinaki P., Orange, Jordan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835774/
https://ncbi.nlm.nih.gov/pubmed/19454694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0804337
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados