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Distinct pathways involving the FK506-binding proteins 12 and 12.6 underlie IL-2-versus IL-15-mediated proliferation of T cells
The molecular basis for the different roles of IL-2 and IL-15 in lymphocyte function has been poorly defined. Searching for differences that underlie the distinct T cell responses to the two cytokines, we observed a marked susceptibility of the IL-15-induced but not of the IL-2-induced proliferation...
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Hoofdauteurs: | , , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
National Academy of Sciences
2003
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC283564/ https://ncbi.nlm.nih.gov/pubmed/14605212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2335979100 |
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