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Survival adjustment of mature dendritic cells by IL-15

The survival of CD8(+)/CD44(hi) memory phenotype T cells depends on an IL-15 activity on nonlymphoid cells. Here, we report that IL-15 and its receptor were induced on dendritic cells (DCs) by a combination of IFN-γ and NF-κB relA inducers. IL-15 conferred in an autocrine loop resistance to apoptosi...

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Detalhes bibliográficos
Main Authors: Dubois, Sigrid P., Waldmann, Thomas A., Müller, Jürgen R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1150852/
https://ncbi.nlm.nih.gov/pubmed/15932944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503360102
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